How to Excipient selection in biologics and vaccines formulation Manufacturer
An excipient plays a significant role in the formulation of molecule pharmaceuticals as these are an integral part of pharmaceutical products. Novel excipients are used in various ways depending on several factors, such as the active ingredient, the route of administration, the dosage form, the target population, and the indication, etc. Additionally, stabilization during processing and storage is a major challenge for the pharmaceutical industry. As a result, biologics and vaccines are vulnerable to degradation by numerous chemical and physical mechanisms. Consequently, the processing and storage of biologics and vaccines require a variety of excipients. GRAS excipients are the most commonly used excipients in biologics and vaccine formulations. It is important to understand interactions between actives and excipients when formulating protein-based therapeutic drugs for stabilization. The complexity of Excipient manufacture is often more pronounced for the development of hig