Process of Tablet Manufacturing and Tablet Packaging | Excipient Manufacturers | ACGGP



In the pharmaceutical industry, tablet manufacturing is a complex method of making solid pharmaceutical dosage forms. Packaging follows with another round of complicated processes. Meanwhile, unit dose packaging has emerged as the most favored form. 

Tablet manufacturing 

The most prominent feature in tablet manufacturing is to ensure the right quantity of active ingredients and excipients. The first step starts with the process of granulation, before pressing or compacting. Here, it is essential to maintain the correct amount of the contents. 

Manufacturers use mainly two processes of granulation: wet granulation and dry granulation. Wet granulation, as the name suggests, uses a liquid binder to agglomerate the contents after properly weighing and mixing the contents. Again this type of granulation has two processes the low-shear and high-shear procedures. 

On the other hand, dry granulation generates granules by compression of the powder. This process is effective when the contents are sensitive to heat and moisture. It is much simpler than wet granulation, thereby more cost-effective as well. 

In the next step, manufacturers blend the granule with lubricants. This prevents the tablet blend from sticking to the equipment. After the lubrication, a highly technical manufacturing operation follows, which includes compaction, presses, and coating. The operation is independent of the types of granulation.

There are four types of coating sugar coating, film coating, microencapsulation, and compression. The coating is usually the last process in the tablet manufacturing process. Sometimes, the process of splitting the pills follows, which is done to make a lower dose of the active ingredient. Further, the process of tablet packaging follows manufacturing.

Tablet Packaging 

This is a comprehensive process of packing and protecting the tablet for storage, distribution, and sale. The primary tablet packaging is physical and barrier protection as well as security.

It follows three types: primary, secondary, and tertiary packaging. The primary step is enclosing the tablet as in strip and blister packages. The next secondary step consists of arranging the blister packs in containers. Finally, the tertiary step comprises packages in large volume for shipping and transportation. 

Final words

For all these highly specialized works, there is always a solution. Several Excipient manufacturers, including those who work contracts, are specializing in different procedures of this industry. Some of them are equipped for custom formulation, packaging, and labeling. 



Location: Grange Business Park, Skule Hill,, Grange, Fedamore, Co. Limerick, Ireland

Comments

  1. LINUS PROJECTS (INDIA) 12 December 2021 at 10:33

    Linus Projects (INDIA) We are a Professional Turnkey Project Management company. We supply plants and machinery for Lube Oil Blending Plant, Grease Manufacturing Plant, and various other Petrochemical Industries Blending Plant in India

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